There weren't a ton of spreads last week, as FCS games are not real games. Here's the Big 12 and the Top 20 teams with FBS opponents this week:
W. Michigan +38 @ #2 OSU. Total 54, so expected final is 46-8.
#3 Texas -7.5 @ #10 Michigan. Total 43, so expected final is 25-18.
USF +31 @ #4 Alabama. Total 64, so expected final is 47-16.
NIU +28 @ #5 Notre Dame. Total 45, so expected final is 36-8.
MTSU +42 @ #6 Ole Miss. Total 64, so expected final is 53-11.
Boise +19.5 @ #7 Oregon. Total 61, so expected final is 40-21.
BGSU +34.5 @ #8 Penn St. Total 49, so expected final is 42-7.
Buffalo +34.5 @ #9 Mizzou. Total 52, so expected final is 43-9.
Baylor +15 @ #11 Utah. Total 54, so expected final is 35-20
USU +28.5 @ #13 USC. Total 63, so expected final is 46-18
#14 Tennessee -8 @ #24 NCSU. Total 61, so expected final is 34-26.
Houston +29 @ #15 Oklahoma. Total 49, so expected final is 40-10.
Arkansas +7.5 @ #16 OKST. Total 63, so expected final is 35-28
#17 KSU -10 @ Tulane. Total 48, so expected final is 29-19.
#19 KU -5.5 @ Illinois. Total 56, so expected final is 30-25
BYU +11.5 @ SMU. Total 56, so expected final is 34-23.
Pitt +2 @ Cincy. Total 62, so expected final is 32-30.
ISU +2.5 @ #21 Iowa. Total 35, so expected final is 19-16.
SHST +22.5 @ UCF. Total 58, so expected final is 40-18.
CU +7 @ Nebraska. Total 59, so expected final is 33-26.
TTech +2 @ WSU. Total 66, so expected final is 34-32.
MSST +6.5 @ ASU. Total 60, so expected final is 33-27.
There are a couple of lines that make me curious. Arkansas only being a TD dog on the road against OKST and MSST being a TD dog on the road against ASU. I'd bet MSST and OKST in both of those. There might be some value in betting Tulane to cover, as 10 points at home is a pretty big spread, and KSU looked like they had some flaws last week.
The rest of the games are mostly garbage. The only value is betting some of those 4-6 TD underdogs to cover, but I couldn't tell you which ones (although I'd be tempted by USU only because the pig farmer knows how to beat USC).
On the totals, BYU seems high (both teams are runners) and I'd bet ISU/Iowa over, except one of the teams is Iowa. USF/Bama seems high too, I think it may take Bama a little while to get into a groove where they can regularly score 50 with their new HC.
If I had to bet the Utah game, the under feels like the safer bet. I don't think Utah gives up 20, and I think the offense tries to establish the run against Baylor's sub-par DL.